Neuromodulators, such as acetylcholine, dopamine, play critical roles in many cognitive processes. My goal is to better understand neuromodulator signaling in the living brain in relation to animals’ behavior. More specifically, I’m interested in using optical methods (e.g. two-photon imaging) to record neuromodulator dynamics in vivo, and relating them to ongoing behaviors (e.g. spatial navigation). Furthermore, we could perturb these signaling to see how that would change behaviors.